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O2 Concepts Oxlife Liberty2 Portable Oxygen Concentrator: A Complete Guide

O2 Concepts Oxlife Liberty2 Portable Oxygen Concentrator: A Complete Guide

EnhDme-Pro Clinical Respiratory Series
Respiratory Solutions · Portable Oxygen

O2 Concepts Oxlife Liberty2 Portable Oxygen Concentrator: A Complete Guide

A next-generation wearable dual-mode concentrator — continuous flow up to 2.0 LPM in fine 0.25 LPM steps, pulse dosing up to setting 10, up to 2,000 mL/min total output, and GPS-enabled cellular telemetry, all in a ~6.5 lb chassis.

Portable Oxygen Concentrators Clinical Review Updated September 2026

High-acuity ambulatory patients often need more oxygen capacity than a typical wearable concentrator can supply, without giving up portability. The O2 Concepts Oxlife Liberty2 is built to close that gap — a next-generation wearable device with roughly twice the therapeutic capacity of standard wearable portables.

Delivering continuous-flow oxygen from 0.5 to 2.0 LPM in precise 0.25 LPM increments, alongside pulse-dose settings 1 through 10 (8 to 80 mL boluses), the Liberty2 supplies up to 2,000 mL/min total output while remaining small enough to fit under a commercial airline seat.

"Roughly twice the therapeutic capacity of standard wearable portables, in a chassis that still fits under an airline seat."
O2 Concepts Oxlife Liberty2 Portable Oxygen Concentrator

Engineered by O2 Concepts®

The Oxlife Liberty2 is manufactured in the United States by O2 Concepts® and backed by a 3-year limited manufacturer warranty. As a Class II FDA-regulated medical device, it is available strictly by prescription. It represents the next generation of O2 Concepts’ wearable dual-mode line, building on the original Liberty platform with higher output, finer flow increments, and integrated GPS tracking.

0.5–2
LPM continuous flow (0.25 LPM steps)
1–10
Pulse-dose settings
2,000
mL/min max total output
O2 Concepts Oxlife Liberty2 — Product View

O2 Concepts Oxlife Liberty2

Portable · Wearable Dual-Mode

O2 Concepts Oxlife Liberty2

A high-capacity wearable dual-mode portable oxygen concentrator weighing approximately 6.5 lbs, pairing continuous-flow oxygen up to 2.0 LPM (in seven fine-grained 0.25 LPM increments) with pulse-dose settings 1 through 10 (8 to 80 mL boluses per breath). Total volume output reaches up to 2,000 mL/min. Patented Energy Smart Technology® extends battery life up to 4.5 hours per module while permitting simultaneous charging on AC or DC power across all flow settings. Embedded DNA® cellular telemetry with integrated GPS automatically transmits diagnostic logs and real-time location metrics to the provider cloud, and a color LCD interface simplifies setting selection and battery monitoring. FAA-ready for commercial air travel.

Model · Oxlife Liberty2 HCPCS · E1390 / E1392
View Oxlife Liberty2 Product Page →

Complete Spec Sheet

Specification Detail
Brand / Manufacturer O2 Concepts®
Model Oxlife Liberty2
Classification High-Capacity Wearable Dual-Mode Portable Oxygen Concentrator
FDA Status Class II Medical Device — Prescription (Rx) Required
HCPCS Code E1390 (Concentrator) / E1392 (Portable Concentrator)
Delivery Scope Continuous: 0.5–2.0 LPM (0.25 LPM steps) | Pulse: Settings 1.0–10.0 (8–80 mL bolus)
Total Max Output ~2,000 mL/min total oxygen capacity
Telemetry / Location DNA® Cellular Telemetry + embedded GPS tracking
Power / Battery AC 100–240V; DC 12–15V | up to 4.5 hrs runtime (charges while operating)
Weight ~6.5 lbs (2.95 kg); fits under airline seats
Origin / Warranty Made in USA — 3-Year Limited Manufacturer Warranty

Clinical Selection Note: Equipment must be selected according to prescribed flow rate and delivery mode. Always cross-reference device capabilities with your physician’s prescription.

Who Is the Oxlife Liberty2 Built For?

The Liberty2 is best suited to high-acuity ambulatory patients who need more oxygen capacity than a standard wearable portable can supply — its 2,000 mL/min total output and 10 pulse settings support higher-demand prescriptions while keeping the device wearable and airline-compatible. Facilities managing high-value mobile assets also benefit from the integrated GPS tracking, which supports loss and theft recovery without added IT infrastructure. As with any oxygen device, the appropriate delivery mode and setting should be determined by your physician based on your specific prescription.

Prescription Verification Protocol: The O2 Concepts Oxlife Liberty2 is an FDA Class II medical device requiring a valid clinical prescription specifying continuous or pulse-dose oxygen settings. Orders submitted to EnhDme-Pro are held until prescription parameters are verified by our clinical compliance staff. Review our Prescription Policy for submission guidelines.

Adding the Oxlife Liberty2 to the EnhDme-Pro catalog gives physicians and facilities a high-capacity wearable option for patients whose oxygen needs exceed what a standard compact portable can provide.

O2 Concepts Oxlife Liberty2 — Additional View

Frequently Asked Questions

What are the main clinical enhancements of the Liberty2 over the original Liberty model?

The Liberty2 increases continuous flow output to 2.0 LPM (in precise 0.25 LPM steps), expands pulse-dose settings to setting 10 (8–80 mL boluses), increases total capacity to 2,000 mL/min, and adds integrated GPS location tracking to the DNA® cellular platform.

How does the integrated GPS functionality protect facility assets?

The embedded GPS hardware operates through the DNA® cellular network, transmitting real-time geographic location coordinates to the provider cloud dashboard to assist facilities in asset tracking and theft recovery.

What prescription documentation is required prior to order dispatch?

Per FDA Class II medical device regulations, orders for the O2 Concepts Oxlife Liberty2 require a valid prescription or medical license specifying continuous or pulse-dose oxygen settings prior to compliance verification and shipment release.

This clinical content is provided for informational and educational purposes and does not constitute formal medical advice. Healthcare providers and patients must verify device suitability against specific physician prescriptions. Technical specifications are subject to manufacturer updates. This product can expose you to chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm — for more information, visit www.P65Warnings.ca.gov.
Providing reliable, clinical-grade respiratory solutions for enhanced patient care.
About the Author
Kevin Lambing, CDME

Kevin Lambing, CDME

Kevin Lambing, CDME is the CEO and founder of EnhDme-Pro (enhdme-pro.com). As a Certified Durable Medical Equipment Specialist with over two decades of experience in clinical respiratory distribution, Kevin leads EnhDme-Pro in providing high-grade medical equipment and technical education to healthcare providers and clinical institutions nationwide.

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