Skip to content
Mckesson 5L Concentrator

McKesson 5 Liter Compact Oxygen Concentrator with OSD: A Complete Guide

EnhDme-Pro Clinical Respiratory Series
Respiratory Solutions · Stationary Oxygen

McKesson 5 Liter Compact Oxygen Concentrator with OSD: A Complete Guide

A space-efficient stationary concentrator built for institutional and long-term care bed placement — continuous flow from 0.5 to 5.0 LPM with real-time purity monitoring via McKesson's integrated OSD sensor.

Oxygen Concentrators Clinical Review Updated September 2026

For standard continuous-flow oxygen prescriptions in institutional or long-term care settings, a reliable, space-efficient 5-liter unit is often the right fit — no more capacity than the patient needs, and a compact footprint that's easy to place bedside. The McKesson 5 Liter Compact Oxygen Concentrator with OSD (Model 146-525DS) is built for exactly that role.

Delivering continuous-flow oxygen from 0.5 to 5.0 LPM at 93% (±3%) purity, the unit's integrated Oxygen Sensing Device (OSD®) continuously verifies output concentration in real time, giving care staff automated compliance monitoring without manual spot-checks.

"Automated, real-time purity monitoring in a compact footprint built for standard bed placement."
McKesson 5 Liter Compact Oxygen Concentrator with OSD

Distributed Under the McKesson Brand

The 146-525DS is distributed under the McKesson Brand and backed by the manufacturer's standard limited warranty. As a Class II FDA-regulated medical device, it is available strictly by prescription.

0.5–5
LPM continuous flow range
93%
Oxygen purity (±3%)
OSD®
Integrated real-time purity sensor

McKesson 5 Liter Compact Oxygen Concentrator (146-525DS)

Stationary / Compact

McKesson 5-Liter Compact Oxygen Concentrator with OSD

A stationary oxygen concentrator built for continuous, long-term oxygen therapy across institutional care settings, long-term care facilities, and home health fleets. Delivers continuous flow from 0.5 to 5.0 LPM at an average concentration of 93% (±3%), with an integrated solid-state OSD® sensor continuously verifying output purity. Features an intuitive control panel, built-in diagnostic alarms for pressure faults, low purity, power outages, and system errors, a low-profile cabinet for space-saving bed placement, and a low-noise pneumatic system designed to minimize acoustic disruption during overnight therapy.

Model 146-525DS · Compact Series HCPCS · E1390
View McKesson 5L Concentrator Page →

Complete Spec Sheet

Specification Detail
Brand / Distributor McKesson Brand
Model / SKU 146-525DS
Classification Compact Stationary Oxygen Concentrator
FDA Status Class II Medical Device — Prescription (Rx) Required
HCPCS Code E1390
Flow Range 0.5–5.0 LPM Continuous Flow
Oxygen Purity 93% (±3%) across all output settings
Purity Monitor Integrated OSD® — continuous solid-state oxygen sensing
Power 115 VAC / 60 Hz standard electrical outlet
Cabinet Design Compact stationary housing with integrated handles
Warranty Standard Manufacturer Limited Warranty

Clinical Selection Note: Equipment must be selected according to prescribed flow rate and delivery requirements. Always cross-reference device capabilities with your physician's prescription.

Who Is the McKesson 5L Concentrator Typically Prescribed For?

This unit is well suited to standard continuous-flow oxygen prescriptions in institutional care settings, long-term care facilities, and home health fleets standardizing on a dependable, space-efficient 5-liter asset. Its automated OSD purity monitoring and low-noise operation also make it a fit for overnight resident care where acoustic disruption is a concern. As with any oxygen device, the appropriate flow rate should be determined by your physician based on your specific prescription.

Prescription Verification Protocol: The McKesson 5 Liter Compact Oxygen Concentrator is an FDA Class II medical device requiring a valid clinical prescription. Orders submitted to EnhDme-Pro are held until prescription parameters are verified by our clinical compliance staff. Review our Prescription Policy for submission guidelines.

Adding the McKesson 5L Compact Concentrator to the EnhDme-Pro catalog gives facilities a dependable, space-efficient option for standard continuous-flow bed placements.

McKesson Oxygen Concentrator — Clinical Setting

Frequently Asked Questions

How does the built-in OSD (Oxygen Sensing Device) support clinical compliance?

The OSD continuously monitors the output purity of generated oxygen in real time. If purity falls below clinical effectiveness standards, the device immediately triggers visual and audible system alarms to alert staff.

What is the HCPCS billing code for the McKesson 146-525DS concentrator?

The standard HCPCS billing descriptor for this 5-liter stationary continuous-flow oxygen concentrator is E1390.

What prescription documentation is required before shipping?

Per FDA Class II medical device regulations, orders for the McKesson 5L Oxygen Concentrator require a valid prescription or medical license specifying continuous-flow oxygen settings prior to compliance verification and order dispatch.

This clinical content is provided for informational and educational purposes and does not constitute formal medical advice. Healthcare providers and patients must verify device suitability against specific physician prescriptions. Technical specifications are subject to manufacturer updates. This product can expose you to chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm — for more information, visit www.P65Warnings.ca.gov.
Providing reliable, clinical-grade respiratory solutions for enhanced patient care.
About the Author
Kevin Lambing, CDME

Kevin Lambing, CDME

Kevin Lambing, CDME is the CEO and founder of EnhDme-Pro (enhdme-pro.com). As a Certified Durable Medical Equipment Specialist with over two decades of experience in clinical respiratory distribution, Kevin leads EnhDme-Pro in providing high-grade medical equipment and technical education to healthcare providers and clinical institutions nationwide.

Previous article Drive DeVilbiss 10 Liter High-Flow Oxygen Concentrator (1025DS): A Complete Guide
Next article CAIRE SeQual Eclipse 5 Portable Oxygen Concentrator — 2 Battery Package: A Complete Guide

Compare products

{"one"=>"Select 2 or 3 items to compare", "other"=>"{{ count }} of 3 items selected"}

Select first item to compare

Select second item to compare

Select third item to compare

Compare